Sex differences in calcium channel

Class differences in calcium-channel blockers in vasospastic angina.

oronary artery spasm is an important mechanism in ischemic heart disease. Vasospastic angina (VSA) is not uncommon in Far-east Asia, including Japan and Korea, than in Western countries, for genetic as well as environmental reasons.1–5 However, it has been given little attention by many cardiologists and there are still many controversies about both the methodology of the pharmacological provoc...

The role of calcium channel blockers in wound healing

Wound healing is a natural response to restore the injured tissue to normal. Wound healing is also complicated process involving different cellular, molecular and biochemical mechanisms and various types of cytokines and growth factors. Calcium channel blockers belong to cardiovascular medicine and administrated to treatment of hypertension, angina and cardiac arrhythmia because of vasodilatory...

Effect of Calcium Channel Blockers on Intraocular Pressure in Rabbits

The objective of the study was to evaluate the antiglaucoma effect of calcium channel blockers diltiazem and verapamil. Albino rabbits were used and chronic glaucoma was induced in them using freshly prepared 150 units of alphachymotrypsin. 0.1 mL of drug solution was administered topically into the left eye whereas the right served as control. The pressure recording was carried out at 15, 30, ...

A simulation study of calcium release channel

The IP3R calcium release channel has been simulated using a stochastic simulation algorithm (SSA;Gillespie algorithm) and De young-Keiser model. A set of different concentration for Cat' and IP3 havebeen used. Considering the Number of molecules in each state, a non linear behavior of the system can beseen clearly. The inhibiting role of the Ca+2 on the open state (X110) has been studied. The d...

sex differences in acute myocardial infarction